Apparatus and method for measuring osmotic pressure in situ

Details Apparatus and method for measuring osmotic pressure in situ Apparatus and method for measuring osmotic pressure in situ

1984-11-20

1986-08-05

Howell, Kyle L.

Surgery

Truss

Pad

128637, 128673, 128748, 73 643, A61B 500

Patent

active

046036997

ABSTRACT:
A multiple-lumen Swanz-Ganz catheter is disclosed wherein said first and second lumens are connected to an osmotic pressure sensor and a third lumen is connected to a hydrostatic pressure sensor. First and second lumens are fluidly continuous, connected through six hollow fibrils. Pressure in the first and second lumens is added to the pressure of the third lumen to determine colloid osmotic pressure.
The fibrils are made of a cellulose acetate material permeable to substances having a molecular weight less than 30,000 and filled with nylon filaments. The fibrils are exposed to the bloodstream through a port in the catheter which also provides an external opening for the third lumen. Fluid in the fibrils is pulsed to remove debris from the surfaces of the fibrils 16. The surfaces of the fibrils are also flushed periodically with physiological saline solution from the third lumen to prevent obstruction. The catheter is held in place by a flotation balloon.

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An Intravascular Protein Osmometer, by John W. Henson and Robert A. Brace, American Journal of Physiology, 244 (Heart Circ. Physiol., 13): H726-H729, 1983.

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