Preparation of hydrazidines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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C07C12302

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044436297

ABSTRACT:
A one-step process for the preparation of hydrazidines of the general formula ##STR1## in which R represents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group or an optionally substituted aralkyl group, or their acid addition salts, in high yield, comprises reacting appropriate amidines or their acid addition salts with hydrazine in solvents at reduced pressure and at temperatures between -80.degree. C. and +100.degree. C., the reaction being effected in the presence of water present in the solvent and/or in the hydrazine by employing it as hydrazine hydrate. The hydrazidines of formula (I) and their salts are valuable intermediates in heterocyclic chemistry, for example for the synthesis of herbicidally active as-triazinones.

REFERENCES:
Journal of Heterocyclic Chemistry, vol. 12, No. 6, pp. 1143-1153.
Justus Liebigs Annalen der Chemie, vol. 749, 1971, pp. 16-23.
Justus Liebigs Annalen der Chemie, 1975, pp. 1120-1123.

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