Process for the production of carnitine amide

Details Process for the production of carnitine amide Process for the production of carnitine amide

1982-01-20

1984-04-17

Waltz, Thomas A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564197, 564198, 564201, C07C10206, C07C103183

Patent

active

044436270

ABSTRACT:
Process for the production of carnitine amide in the form of a chloride. The carnitine ethyl ester is obtained by reaction of 4-chloroacetoacetic acid ethyl ester with trimethyl amine and the subsequent hydrogenation is carried out with the help of a Pt/C catalyst. Such carnitine ethyl ester, without isolating it, is reacted with ammonia in an autoclave at -30.degree. to +10.degree. C. Everything is heated to 40.degree. to 80.degree. C. The mixture is stirred at such temperature at an ammoniac pressure of 8 to 24 atu. The product is filtered after cooling it to ambient temperature and counterbalancing the excess pressure. The product is then washed with alcohol and subsequently dried at 30.degree. to 50.degree. C. and at a pressure of 15 to 25 torr.

REFERENCES:
patent: 2087565 (1937-07-01), Balle et al.
patent: 3072722 (1963-01-01), Aspergren et al.
patent: 3096244 (1963-07-01), Ehrhart et al.
patent: 3155658 (1964-11-01), Rogier
patent: 3462485 (1969-08-01), Binon et al.
patent: 4254053 (1981-03-01), de Witt et al.

Affiliated with

Also associated with

Rating

Process for the production of carnitine amide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of carnitine amide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of carnitine amide will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-96328