Aminophenyltetralin compounds

Details Aminophenyltetralin compounds Aminophenyltetralin compounds

1976-05-27

1977-08-30

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2605011, 26050111, 26050121, 260566R, 260566B, 260566A, 260566F, 260578, 260579, 424316, 424330, C07C 8764

Patent

active

040454886

ABSTRACT:
A series of novel 4-phenyl-1,2,3,4-tetrahydro-1-naphthylamines, including their pharmaceutically acceptable acid addition salts and their cis- and trans-isomers, have been prepared. The trans-isomers are useful in the field of mental health as antidepressant agents and/or as psychomotor stimulants. The trans-isomer of N-methyl-4-phenyl-1,2,3,4-tetrahydro-1-naphthylamine represents a preferred embodiment.

REFERENCES:
patent: 3347870 (1967-10-01), Rutschmann et al.
patent: 3704323 (1972-11-01), Krapcho
patent: 3904691 (1975-09-01), Carnmalm et al.
Geigy, "Chemical Abstracts", vol. 67, p. 2084, Section No. 21854e (1967).

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