Cyanoprostaglandins

Details Cyanoprostaglandins Cyanoprostaglandins

1976-08-06

1977-08-30

Brust, Joseph P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2604488R, 260940, 260465D, 424304, 542430, 542429, C07C12148

Patent

active

040454657

ABSTRACT:
The 19-cyano-20-nor derivatives of prostaglandins E.sub.1 and E.sub.2, and certain esters thereof, are bronchodilatory agents, useful in the treatment of bronchial asthma, bronchitis, pneumonia and emphysema. The 19-cyano-20-nor derivatives of prostaglandins E.sub.1 and E.sub.2, and certain esters thereof, which also have protecting groups on the hydroxy groups at C-11 and C-15 are useful intermediates for the preparations of the bronchodilatory agents of this invention.

REFERENCES:
patent: 3723423 (1973-03-01), Andersen et al.
patent: 3890351 (1975-06-01), Taub

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