Synthesis of alpha-aminonitriles

Details Synthesis of alpha-aminonitriles Synthesis of alpha-aminonitriles

1991-04-15

1992-12-08

Brust, Joseph P.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

546330, 5483361, 549 74, 549492, 558332, 558408, 558409, 558432, 558433, 558434, 558430, 558452, C07C25330

Patent

active

051699737

ABSTRACT:
Alpha-aminonitriles can be synthesized by the reaction, at ambient temperature without use of catalyst, of essentially stoichiometric amounts of amine, aldehyde (either monoaldehyde or dialdehyde) and trimethylsilyl cyanide.

REFERENCES:
patent: 4551526 (1985-11-01), Mai et al.
patent: 4996346 (1991-02-01), Gibson et al.
Pandya, et al., Amer. Chem. Soc., Polymer Preprints, 30, pp. 206-207, (1989).
Gibson, et al., Amer. Chem. Soc., Polymer Preprints, 30, pp. 208-209, (1989).
Sanfran, et al., Russ. chem. Rev. 58: pp. 148-162, (1989).
Gassman, et al., Tetrahedron Letters (1978), No. 40, pp. 3773-3776.
Mai, et al., Tetrahedron Letters (1984), 25, No. 41, pp. 4583-4586.
Mai, et al., Synthetic Communications, 15(2), (1985), pp. 157-163.
Mai, et al., Organic Preparations & Procedures Int., 17, (1985), pp. 183-186.

Affiliated with

Also associated with

Rating

Synthesis of alpha-aminonitriles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of alpha-aminonitriles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of alpha-aminonitriles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-961945