Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for p

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549273, 549292, 549294, 549518, 549561, C07D31906

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active

052568008

ABSTRACT:
There are provided novel and optically active 2,2-dimethyl-1,3-dioxin-4-ones which are useful as starting materials for physiologically active compounds, functional materials or the like. Furthermore, a method for preparing an optically active compound comprises reacting a racemic 1,3-dioxin-4-one with vinylacetate in the presence of lipase to resolve the racemic compound into optically active compound represented by the formula (3) ##STR1## and an optically active compound represented by the formula (4) ##STR2## which is an antipode of the compound represented by the formula (3).

REFERENCES:
Sakaki et al.; J.C.S., C.C.; 1991; pp. 434-435.
Sato et al; Chem. Abst.; 1992; 41376.
Sakaki et al.; Tetrahedron; Asymmetry; vol. 2 No. 5; 1991; pp. 343-346.
Sakaki et al., Chemistry Letters, No. 6, Jun. 1990, pp. 901-904.
Chisso Corp., Patent Abstracts of Japan, vol. 14, No. 439 (C-761), 19 Sep. 1990 [JP-A-2 171 192 2 Jul. 1990].
Sakaki et al., Tetrahedron, vol. 47, No. 32, pp. 6197-6214 (1991).

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