Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-12-19
2000-12-05
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 435 75, 435 771, 435 772, 435 78, 435 795, 435960, 435962, 435971, 435973, 436518, 436523, 436528, 436535, 436538, 436811, 436819, G01N 33533
Patent
active
061565210
ABSTRACT:
The invention relates in part to methods and compositions for identifying the presence, measuring the amount, stabilizing, and facilitating recovery of troponin complexes or individual troponin isoforms in a sample.
REFERENCES:
patent: 4933275 (1990-06-01), Wands et al.
patent: 5051356 (1991-09-01), Warren, III et al.
patent: 5143852 (1992-09-01), Valkirs et al.
patent: 5210020 (1993-05-01), Kondo et al.
patent: 5246001 (1993-09-01), Ohman et al.
patent: 5290678 (1994-03-01), Jackowski
Luo et al., "Troponin T and Ca2+ dependence of the distance between Cys48 and Cys 133 of Troponin I in the ternary troponin complex and reconstituted thin filaments," Biochemistry 36:11027-11035 (1997).
Microparticle Reagent Optimization, Seradyn Inc., p.91-97 (1994).
Cummins et al., "Cardiac Specific Troponin-I Radioimmunoassay in the Diagnosis of Acute Myocardial Infarction," American Heart Journal 113:1333-1344 (1987).
Katus et al., "Intracellular Compartmentation of Cardiac Troponin T and Its Release Kinetics in Patients with Reperfused and Nonreperfused Myocardial Infarction," Am. J. Cardiol. 67:1360-1367 (1991).
Zot et al., "Structural Aspects of Troponin-Tropomyosin Regulation of Skeletal Muscle Contraction," Am. Rev. Biophys. Biophys. Chem 16:535-559 (1987).
Harlow and Lane, Index, Antibodies, A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (1988).
Borrebaeck ed., Index, Antibody Engineering: A Practical Approach, Oxford university Press, Oxford (1995).
Leavis et al., "Calcium Binding to Cardiac Troponin C.sup.1,2," Arch. Biochem. Biophys., 186:411-415 (1978).
Cummins et al., "Troponin I from Human Skeletal and Cardiac Muscles," Biochem. J., 171:251-259 (1978).
Blechner et al., "4Ca.sup.2+ .circle-solid.Troponin C Forms Dimers in Solutions at Neutral pH That Dissociate upon Binding Various Peptides: Small-Angle X-ray Scattering Studies of Peptide-Induced Structural Changes," Biochem., 31:11326-11334 (1992).
Olah et al., "Troponin I Encompasses an Extended Troponin C in the Ca.sup.2+ -Bound Complex: A Small-Angle X-ray and Neutron Scattering Study," Biochem., 33:8233-8239 (1994).
Ball et al., "Isoform Specific Interactions of Troponin I and Troponin C Determine pH Sensitivity of Myofibrillar Ca.sup.2+ Activation," Biochem., 33:8464-8471 (1994).
Liao et al., "Coupling of Calcium to the Interaction of Troponin I with Troponin C from Cardiac Muscle," Biochem., 33:12729-12734 (1994).
Olah et al., "A Model Structure of the Muscle Protein Complex 4Ca.sup.S+ .circle-solid.Troponin C.circle-solid.Troponin I Derived from Small-Angle Scattering Data: Implications for Regulation," Biochem., 33:12800-12806 (1994).
Liao et al., "Time-resolved tryptophan emission study of cardiac troponin I," Biophys. J., 63:986-995 (1992).
Pluskal et al., "Immobilon.TM. PVDF Transfer Membrane: A new Membrane Substrate For Western Blotting of Proteins," BioTechniques, 4:272-283 (1986).
Burtnick et al., "The isolation and characterization of the tropomyosin binding component (TN-T) of bovine cardiac troponin," Can. J. Biochem., 54:546-553 (1976).
Pearlstone et al., "The interaction of rabbit skeletal muscle troponin-T fragments with troponin-I," Can. M. Biochem. Cell. Biol., 63:212-218 (1985).
Anderson et al., "Troponin T isoform Expression in Humans," Circul. Res. 69:1226-1233 (1991).
Katus et al., "Diagnostic Efficiency of Troponin T Measurements in Acute Myocardial Infarction," Circulation 83:902-912 (1991).
Zabel et al., "Analysis of Creatine Kinase, CK-MB, Myoglobin, and Troponin T Time-Activity Curves for Early Assessment of Coronary Artery Referfusion After Intravenous Thrombosis," Circulation 87:1542-1550 (1993).
Wu et al., "Creatine Kinase MB isoforms in Patients with Skeletal Muscle Injury: Ramifications for Early Detection of Acute Myocardial Infarction," Clin. Chem., 38:2396-2400 (1992).
Collins et al., "Early Diagnosis of Acute Myocardial Infarction with Use of a Rapid Immunochemical Assay of Creatine Kinase MB Isoenzyme," Clin. Chem. 39:1725-1728 (1993).
Adams et al., "Comparable Detection of Acute Myocardial Infarction by Crfatine Kinase MB Isoenzyme and Cardiac Troponin I," Clin. Chem. 40:1291-1295 (1994).
Bhayana et al., "Discordance Between Results for Serum Troponin T and Troponin I in Renal Disease," Clin. Chem. 41:312-317 (1995).
Vallins et al., "Molecular cloning of human cardiac troponin I using polymerase chain reaction," FEBS Letters 270:57-61 (1990).
Bhavsar et al.,"Developmental expression of troponin I isoforms in fetal human heart," FEBS Letters 292:5-8 (1991).
Townsend et al., "Human Cardiac Troponin T: Identification of Fetal Isoforms and Assignment of the TNNT2 Locus to Chromosole 1q," Genomics 221:311-316 (1994).
MacGeoch et al., "The human cardiac troponin I locus: assignment to chromosome 19p13.2-19q13.2," Hum. Genet. 88:101-104 (1991).
Stull et al., "Phosphorylation of Cardiac Troponin by Cyclic Adenosine 3':5'-Monophosphate-dependent Protein Kinase*," J. Biol. Chem. 252:851-857 (1977).
Horwitz et al., "Interaction of Troponin Subunits," J. Biol. Chem. 254:350-355 (1979).
Pearlstone et al., Effects of Troponin-I Plus -C on the Binding of Troponin-T and Its Fragments to .alpha.-Tropomyosin, J. Biol. Chem. 258:2534-2542 (1983).
Byers et al., "Hydrodynamic Properties of Bovine Cardiac Troponin-I and Troponin-T*," J. Biol. Chem. 258:2951-2954 (1983).
Schreier et al., "Cloning, Structural Analysis, and Expression of the Human Slow Twitch Skeletal Muscle/Cardiac Troponin C Gene*," J. Biol. Chem. 265:21247-21253 (1990).
Sai-Ming Ngai et al., "Biologically Important Interactions between Synthetic Peptides of the N-terminal Region of Troponin I and Troponin C*," J. Biol. Chem. 267:15715-15723 (1992).
Huse et al., "Application of a Filamentous Phage pVIII Fusion Protein System Suitable for Efficient Production, Screening, and Mutagenesis of F9(ab) Antibody Fragments," J. Immunol. 149:3914-3920 (1992).
Potter, "Preparation of Troponin and Its Subunits," Methods in Enzymol. 85:241-263 (1982).
Wilkinson et al., "Comparison of amino acid sequence of troponin I from different striated muscles," Nature 271:31-35 (1978).
Metzger et al., "Skeletal troponin C reduces contractile sensitivity to acidosis in cardiac myocytes from transgenic mice," Proc. Natl. Acad. Sci. USA 90:9036-9040.
Bodor et al., "Development of Monoclonal Antibodies for an Assay of Cardiac Troponin-I and Preliminary Results in Suspected Cases of Myocardial Infarction," Clin. Chem. 38(11):2203-2214 (1992).
Katus et al., "Development and In Vitro Characterization of a New Immunoassay of Cardiac Troponin T," Clin Chem. 38(3):386-393 (1992).
Larue et al., "New Monoclonal Antibodies as Probes for Human Cardiac Troponin I: Epitopic Analysis with Synthetic Peptides," Molecular Immunology 29(2):271-278 (1992).
Larue et al., "Cardiac-Specific Immunoenzymometic Assay of Troponin I in the Early Phase of Acute Myocardial Infarction," Clin. Chem. 39(6):972-979 (1993).
Takahasi et al., "Development and Characterization of Monoclonal Antibodies Sepcific for Human Cardiac Troponin I," Clin. Chem. 39(6):1133 (1993).
SIGMA Catalog (1992).
Microparticle Reagent Optimization, Seradyn Inc., p. 91-97.
J. Immunol. 149:3903-3913 (1992).
Anal. Biochem. 162:156-159 (1987).
"Sequences of proteins of immunological interest." vol. 2 5th ed. Cambridge MA. (1991).
"Biochemistry 36" p.11027-11035 (1997).
Buechler Kenneth F.
McPherson Paul H.
Biosite Diagnostics, Inc.
Housel James C.
Nguyen Bao-Thuy L.
LandOfFree
Methods for the recovery and measurement of troponin complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for the recovery and measurement of troponin complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for the recovery and measurement of troponin complexes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-960327