Method to prepare an improved storage stable neem seed extract

Details Method to prepare an improved storage stable neem seed extract Method to prepare an improved storage stable neem seed extract

1989-06-26

1990-08-07

Rollins, John W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

549383, A61K 3578

Patent

active

049466810

ABSTRACT:
A process for the production of stable azadirachtin solutions comprising extracting ground neem seeds with a solvent having azadirachtin solubility to produce an aqueous-containing azadirachtin extract solution and then adding an effective amount of 3-4 Angstrom molecular sieves to selectively remove water from the extract to yield a storage-stable azadirachtin solution having less than 5% water by volume.

REFERENCES:
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Feuerhake, et al., J. Plant Diseases and Protection, 89(12), pp. 737-747 (1982).
Schroeder, et al., J. Natural Products, 50(2), pp. 241-244 (Mar.-Apr. 1987).
Warthen, Jr., et al., J. Liquid Chromatography, 7(3), pp. 591-598 (1984).
Uebel, et al., J. Liquid Chromatography, 2(6), pp. 875-882 (1979).
Polasa, et al., Fd. Chem. Toxic., 25(10), pp. 763-766 (1987).
Muthusamy, et al., Neem Newsletter, 5(4), Oct.-Dec., p. 48 (1988).
Ladd, Jr., et al., J. Econ. Entomol., 77, pp. 903-905 (1984).
Warthen, Jr., Sci. Ed. Admin., Agric. Rev. & Manuals., Northeastern Series, No. 4, Apr. (1979).
Hawley, Condensed Chemical Dictionary, Tenth Edition, p. 700 (1981).

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