Preparations active against pseudomonas aeruginosa infections an

Details Preparations active against pseudomonas aeruginosa infections an Preparations active against pseudomonas aeruginosa infections an

1987-06-17

1990-08-07

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 514 2, 514 8, 514 21, 530350, 530395, 530403, 530806, 530825, C07K 302, C07K 1504, A61K 3574, A61K 39104

Patent

active

049466771

ABSTRACT:
Preparations active against Pseudomonas aeruginosa Infections, namely vaccines for active immunization as well as preparations containing antibodies and destined for passive protection; as well as methods for the production thereof.
The vaccines contain protective flagellar (H) antigens of the serotype a and b, which consist of monomeric components, each monomeric component is composed of certain amino acids having a certain N-terminal amino acid sequence and has a certain molecular weight. The vaccines are made from purified flagellar (H) antigen solutions. The immunoglobulin-G-containing preparations contain flagellar (H) antibodies obtained from the blood plasma of human donors or mammals immunized with protective flagellar (H) antigens. They can be purified by methods of affinity chromatography.

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