Process for preparing 4-acylamino-2,2,6,6-tetramethylpiperidines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21198

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057288364

ABSTRACT:
Preparation of 4-acylamino-2,2,6,6-tetramethylpiperidines from 4-amino-2,2,6,6-tetramethylpiperidine and acid anhydrides carried out in the presence of carboxylic acids, whereupon the carboxylic acid is eliminated, using water at elevated temperature, from the initially formed carboxylate salt of the 4-acylamino-2,2,6,6-tetramethylpiperidine. In this process, no salt-like by-products arise.

REFERENCES:
patent: 5416215 (1995-05-01), Buschken et al.
Journal of Organic Chemistry, vol. 56, No. 21, pp. 6110-6114, Oct. 11, 1991, Zhenkun MA, et al., "Organic Oxoammonium Salts--A New Convenient Method for the Oxidation of Alcohols to Aldehydes and Ketones".
Chemical Abstracts, vol. 66, No. 13, AN-54758, Mar. 27,1967.

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