Pharmaceutical composition containing R-.alpha.-lipoic acid or S

Details Pharmaceutical composition containing R-.alpha.-lipoic acid or S Pharmaceutical composition containing R-.alpha.-lipoic acid or S

1997-02-03

1998-03-17

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 3120

Patent

active

057287350

ABSTRACT:
Pharmaceutical compositions and processes for their preparation containing R-.alpha.-lipoic acid or S-.alpha.-lipoic acid or pharmaceutically acceptable salts thereof. The pharmaceutical compositions have a cytoprotective activity and are suitable for combatting pain and inflammation.

REFERENCES:
patent: 3577551 (1971-05-01), Murakami et al.
patent: 4705867 (1987-11-01), Giray et al.
patent: 4800044 (1989-01-01), Giray et al.
patent: 4966732 (1990-10-01), Giray et al.
Egan et al., "Radical Scavenging as the Mechanism for Stimulation of Prostaglandin Cyclooxygenase and Depression of Inflammation by Lipoic Acid and Sodium Iodide", Prostaglandins, Dec. 1978, vol. 16, No. 6, pp. 861-869.
Szabo, "Experimental Basis for a Role for Sulfhydryls and Dopamine in Ulcerogenesis: A Primer for Cytoprotection-Organoprotection," Klin Wochernchr (1986) 64 (Suppl VII): 116-122.
Gracyk et al., "Influence of Anti-Inflammatory Agents on the Nonspecific Component of Human Neutrophil Chemotatic Deactivation," Federation Proceedings, Mar. 1, 1980, vol. 39, No. 3, Part I.
Cesobari et al., "Drogas citoprotectoras de la mucosa gastrica, ante la agresion del etanol," Trabajos Originales, Rev. Exp. Enf. Ap. Digest, 7, 3 (329-232), 1988.

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