Process for preparing 3-acyloxymethyl-2-cephem compounds

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602391, C07D50104

Patent

active

040296512

ABSTRACT:
A 3-exomethylenecepham sulfoxide ester is reacted with a mixture of a carboxylic acid of the formula ##STR1## and the corresponding anhydride of said carboxylic acid at a temperature of from about 70.degree. C. to about 130.degree. C. to produce the corresponding 3-acyloxymethyl-.DELTA..sup.2 -cephem. This product is useful as an intermediate in the preparation of antibiotically active cephalosporins.

REFERENCES:
patent: 3883518 (1975-05-01), Ponticello
patent: 3933806 (1976-01-01), Spry

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