Method and use for site-specific activation of substances

Details Method and use for site-specific activation of substances Method and use for site-specific activation of substances

1992-09-15

1993-10-26

Lacey, David L.

Drug, bio-affecting and body treating compositions

Lymphokine

435 7021, 4351722, 435188, 43524027, 530382, 53038825, 5303893, 5303917, 935104, 935107, A61K 39395, C07K 1528

Patent

active

052564134

ABSTRACT:
Disclosed is a method for the in vivo lysis of a thrombus in a host by administration of a conjugate consisting of a monoclonal antibody specific for fibrin coupled to a plasminogen activator such as tissue plasminogen activator, urokinase or streptokinase.

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