Cyclosporin formulations of mono or diglyceride fatty acid

Details Cyclosporin formulations of mono or diglyceride fatty acid Cyclosporin formulations of mono or diglyceride fatty acid

1990-04-12

1991-02-05

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424428, 514 15, 514786, 514885, 514914, A61K 910

Patent

active

049903373

ABSTRACT:
Cyclosporins are useful immunosuppressive, anti-fungal and antiphlogistic agents which are relatively insoluble in water and aqueous fluids (including body fluids). They may be rendered more soluble or dispersible in aqueous media by first dissolving them in at least one mono- or di- glyceride of a C.sub.6 -C.sub.10 fatty acid, and the resulting solution can then easily be emulsified in water or an aqueous fluid.

REFERENCES:
patent: 2865859 (1958-12-01), Lubowe
patent: 3678149 (1972-07-01), Prigal
patent: 4388307 (1983-06-01), Cavanak
patent: 4474751 (1984-10-01), Haslam et al.
patent: 4612193 (1986-09-01), Gordon et al.
patent: 4649047 (1987-03-01), Kaswan
patent: 4659696 (1987-04-01), Hirai et al.
patent: 4670419 (1987-06-01), Uda et al.
patent: 4711902 (1987-12-01), Serno
patent: 4722914 (1988-02-01), Eckert et al.
patent: 4839342 (1989-06-01), Kaswan

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