Antitumor chamigrene derivatives and their methods of use

Details Antitumor chamigrene derivatives and their methods of use Antitumor chamigrene derivatives and their methods of use

1985-09-04

1990-07-17

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

568367, A61K 3112, C07C 49553

Patent

active

049421808

ABSTRACT:
This invention relates to antitumor compositions, and a method for inhibiting, remitting or controlling the growth of tumors or tumor cells utilizing antitumor compositions. More particularly, the antitumor compositions comprise, as active ingredient, an antitumor effective amount of halogenated chamigrenes extracted and derived from red alga and sea hares which diet upon red alga.

REFERENCES:
patent: 4162308 (1979-07-01), Calvin et al.
patent: 4162309 (1979-07-01), Calvin et al.
Bull. Chem. Soc. Jpn., 56 (No. 12), pp. 3824-3826 (1983), M. Suzuki et al.
Tetrahedron Letters, No. 26, 1973, Pergamon Press (GB), A. G. Gonzalez et al., pp. 2381-2384.
Tetrahedron Letters, No. 23, 1974, Pergamon Press (GB), J. A. McMillam et al., pp. 2039-2042.
Tetrahydron Letters, No. 4, 1975, Pergamon Press (GB), S. M. Waraskiewicz et al., pp. 281-284.
Tetrahydron Letters, No. 35, 1976, Pergamon Press (GB), A. G. Gonzaleaz et al., pp. 3051-3054.
Tetrahedron, vol. 35 (1979), Hollenbeak et al., pp. 541-545.
Planta Medica, vol. 44 (1982), Gonzaleaz et al., pp. 44.noteq.46.
Suzuki et al., Bull. Chem. Soc. Jpn, 56(WO. 12), pp. 3824-3826 (1983) (a copy is needed).

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