Biphenyl oxadiazoles and thiadiazoles as angiotensin II antagoni

Details Biphenyl oxadiazoles and thiadiazoles as angiotensin II antagoni Biphenyl oxadiazoles and thiadiazoles as angiotensin II antagoni

1993-02-12

1994-08-16

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514269, 514303, 514312, 514334, 514340, 514342, 514361, 514363, A61K 31435, A61K 3142

Patent

active

053387376

ABSTRACT:
Novel heterocyclic methyl derivatives of biphenyl oxadiazoles and thiadiazoles are described, as well as methods for the preparation of said derivatives and pharmaceutical compositions of the same, which are useful as antagonists of the angiotensin II enzyme and thus useful in treating hypertension, hyperaldosteronism, congestive heart failure, and glaucoma.

REFERENCES:
patent: 4618617 (1986-10-01), Yamamoto
patent: 5086053 (1992-02-01), Brodin et al.
patent: 5100897 (1992-03-01), Allen et al.
patent: 5102897 (1992-04-01), Boschelli et al.

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