Angiotensin II receptor blocking 2,3,6-substituted quinazolinone

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

544284, 544287, A61K 31505, C07D23990, C07D23991

Patent

active

053387368

ABSTRACT:
This disclosure describes novel 2,3,6-substituted quinazolinones of the formula: ##STR1## where R.sup.6, R.sup.5 and R are described in the specification which have activity as angiotensin II (AII) antagonists.

REFERENCES:
patent: 5202322 (1993-04-01), Allen
patent: 5204354 (1993-04-01), Chakravarty et al.
patent: 5238942 (1993-08-01), Chakravarty et al.
patent: 5240928 (1993-08-01), Allen et al.
patent: 5281602 (1994-01-01), Newman
patent: 5281603 (1994-01-01), Venkatesan
patent: 5281604 (1994-01-01), Levin
patent: 5284852 (1994-02-01), Levin
patent: 5284853 (1994-02-01), Levin
patent: 5286729 (1994-02-01), Levin
patent: 5288720 (1994-02-01), Albright
patent: 5290780 (1994-03-01), Venkatesan
patent: 5292734 (1994-03-01), Levin
patent: 5292742 (1994-03-01), Venkatesan
patent: 5294611 (1994-03-01), Venkatesan
patent: 5294617 (1994-03-01), Venkatesan
patent: 5296480 (1994-03-01), Newman
U.S. Pat. Appl. No. 08/052,945 Levin filed Apr. 23, 1993.

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