Topical treatment of seborrheic dermatitis with ketoconazole

Details Topical treatment of seborrheic dermatitis with ketoconazole Topical treatment of seborrheic dermatitis with ketoconazole

1989-01-27

1990-07-17

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514864, A61K 3150, A61K 31495

Patent

active

049421620

ABSTRACT:
A method is provided for treating psoriasis and seborrheic dermatitis in humans by topical application of an effective, lesion reducing amount of ketoconazole to affected areas.

REFERENCES:
patent: 4172947 (1979-10-01), Warner et al.
patent: 4205071 (1980-05-01), Durant et al.
patent: 4358449 (1982-11-01), Heeres et al.
"Treatment of Pityriasis Capitis (Dandruff) with Econazole Nitrate", Acta Dermatovener (Stockholm), vol. 57, pp. 77-80 (1977)-Article discusses a dandruff treatment with Econazole Nitrate and discusses a casual relationship between fungal infestation and dermatological disorders.
"Activation of the Alternative Pathway of Complement by Malassezia Ovalis (Pityrosporum Ovale)", Mycopathologia, vol. 70.3, pp. 187-191 (1980)-Article discusses a mechanism for seborrheic dermatitis.
"Effect of Topical Applications of Heavy Suspensions of Killed Malassezia Ovalis on Rabbit Skin", Mycopathologia, vol. 72, pp. 147-154 (1980)-Article discusses experimentation leading to an explanation of human psoriasis.
"Sabouraud and Rivolta were Right-Seborrheic Dermatitis is Microbial", Cosmetics and Toiletries, Aug., 1981-Article discusses a mechanism for seborrheic dermatitis.
Chemical Abstracts, 97:84718d (1982).
Physicians Desk Reference (PDR), 34th ed., 1980, p. 1561.

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