Preparation of halofluoroalkyl ethers

Details Preparation of halofluoroalkyl ethers Preparation of halofluoroalkyl ethers

1981-08-26

1983-12-27

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568683, 568669, 568684, 568685, C07C 4116

Patent

active

044232497

ABSTRACT:
Alkyl or aryl 1,1-difluoroalkyl ethers, e.g., 1,1,2-trifluoro-2-chloro-2-iodoethyl phenyl ether, are prepared by reacting an alkoxide or phenoxide with a 1,1-difluoro-1,2-dihaloethane (with the proviso that halo is not fluoro and at least one of the halo substituents is bromo or iodo) in an organic solvent at temperatures ranging from about -30.degree. C. to about 100.degree. C. These compounds may be dehalogenated with zinc to form the corresponding vinyl ethers.
The reaction of halogen derivatives of fluorocarbons with nucleophiles is dramatically facilitated by a bromo or iodo substituent in the beta position.

REFERENCES:
patent: 3926989 (1975-12-01), Rebsdat et al.
patent: 4377711 (1983-03-01), Rico et al.
Tarrant et al., J.A.C.S., vol. 75 (1953) 932-934.
Corley et al., J.A.C.S., vol. 78 (1956) 3489-3493.
Scipioni et al., (English Translation) Ann. Chim. Rome, 57(7) (1967) 817-824.
Banus et al., J. Chem. Soc. (1951) 60-64.

Affiliated with

Also associated with

Rating

Preparation of halofluoroalkyl ethers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of halofluoroalkyl ethers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of halofluoroalkyl ethers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-948803