Process for preparing N-(methyl-sulfonyl)-1,2,8,8a-cyclopropa[c]

Details Process for preparing N-(methyl-sulfonyl)-1,2,8,8a-cyclopropa[c] Process for preparing N-(methyl-sulfonyl)-1,2,8,8a-cyclopropa[c]

1982-02-08

1983-12-27

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548433, C07D48704

Patent

active

044232284

ABSTRACT:
Novel antibacterially-active compound, 1,2,8,8a-cyclopropa[c]benzo[1,2-b:-4,3-b']dipyrol-4(5H)-one, prepared by a novel chemical process. This compound, as well as antibacterially-active intermediates, can be used to eradicate or control susceptible bacteria, for example, B. subtilis, K. pneumonia, S. lutea, S. aureus, and M. avium.
Included is a process for the preparation of an intermediate compound of the formula ##STR1##

REFERENCES:
patent: 4169888 (1979-10-01), Hanka et al.
Martin, D. G., et al., J. Antibiot. 33, 902 (1980).
W. Theilheimer, Synthetic Methods of Organic Chemistry, vol. 31, No. 499 (1977).
R. Appel, Angew. Chem. Internatl., Edit., vol. 14 (1975), No. 12, 801-811.

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