Process for the manufacture of human insulin

Details Process for the manufacture of human insulin Process for the manufacture of human insulin

1975-12-19

1977-06-14

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, C07C10352

Patent

active

040296423

ABSTRACT:
A process for the manufacture of human insulin by the condensation of porcine des-B.sub.23-30 octapeptide insulin with a peptide and subsequent splitting-off of the protective groups by treatment with trifluoroacetic acid or with alkali.

REFERENCES:
patent: 3847892 (1974-11-01), Wang
patent: 3903068 (1975-09-01), Ruttenberg
patent: 3907765 (1975-09-01), Wang
Scientia Sinica, vol. 16, (1973), 61-70.
Hoppe--Seyler's Z. Physiol. Chem., Bd. 357, 5, 187-200, (1976).
Human Insulin: (1972), pp. 623-626.

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