Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-05-30
1982-02-16
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A01N 4500
Patent
active
043159257
ABSTRACT:
The invention relates to a novel method of administering the natural female sex hormones, 17 .beta.- estradiol and progesterone, to achieve enhanced bioavailability thereof. The invention further relates to novel dosage forms of 17 .beta.- estradiol and/or progesterone which are adapted for nasal administration, such as solutions, suspensions, gels and ointments. The dosage forms containing a combination of 17 .beta.-estradiol and progesterone are particularly useful as contraceptives, while the dosage forms containing only one of the hormonal components find utility in the treatment of conditions such as menopause, menstrual disorders, etc., which are known to respond to administration of a natural or synthetic female hormone.
REFERENCES:
patent: 3733407 (1973-05-01), Segre
patent: 3942641 (1976-03-01), Segre
patent: 4071623 (1978-01-01), van der Vies
patent: 4145416 (1979-03-01), Lachnit-Fixson et al.
Brown et al., "British Medical Journal", Mar. 4, 1972, pp. 585-590.
Bawarshi Rima
Hirai Shin-ichiro
Hussain Anwar A.
Roberts Elbert L.
University of Kentucky Research Foundation
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