Intermediate for the preparation of 19-nor vitamin D compounds

Details Intermediate for the preparation of 19-nor vitamin D compounds Intermediate for the preparation of 19-nor vitamin D compounds

1995-05-16

1997-01-28

Prior, Kimberly J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549414, 549415, 549416, 549420, 549421, 549429, 549472, 549473, 549475, 556437, 556443, 568445, 568612, 568665, 568819, 568833, 568376, 560126, C07D30900, C07F 718, C07C 4728

Patent

active

055979327

ABSTRACT:
The invention is drawn to a compound having the following formula ##STR1## in which X.sup.1 and X.sup.2, which may be the same or different, represent hydrogen or a hydroxy-protecting group, X.sup.4 is hydrogen, A is selected from --COOAlkyl and CH.sub.2 OH, and B is a hydroxy group, or A and B, when taken together, represent an oxo group. These compounds are useful as intermediates in the production of 19-nor vitamin D derivatives.

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Lythgoe, Synthetic Approaches to Vitamin D and its Relatives, Chem. Soc. Review, 9, 449-474, 1983.

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