Process for preparing cannabichromene

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424283, C07D31158

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active

043158625

ABSTRACT:
The preparation of cannabichromene (CBC) and homologues thereof by condensation of citral with a substituted resorcinol in the presence of a primary amine, and the use of these compounds to induce hypothermia and reduce inflammation in mammals, is disclosed. Preferably, the cannabichromene is administered as a novel composition, in combination with a pharmaceutically acceptable diluent carrier. A new compound 2-methyl-2(4-methyl-pent-3-enyl)-5-hydroxy-7-methylchromene (CBC-C.sub.1).

REFERENCES:
Kane et al., JACS, 90, 6551 (1968).
Crombie et al., J. Chem. Soc. (C), 796 (1971).
Crombie et al., J. Chem. Res. S (Synopses), 1977, (5), 114-115, (C.A. 87:102470s).

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