Oximino-substituted cephalosporin compounds

Details Oximino-substituted cephalosporin compounds Oximino-substituted cephalosporin compounds

1981-10-02

1983-04-12

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 22, 544 25, C07D50140, A61K 31545

Patent

active

043797873

ABSTRACT:
Broad spectrum cephalosporin antibiotics represented by the formula ##STR1## wherein R is an amino-substituted oxazole, oxadiazol, or isoxazole heterocyclic, R' is C.sub.1 -C.sub.4 alkyl, a carboxysubstituted alkyl or cycloalkyl group, etc., and .sup..sym. R.sub.1 is an oximino-substituted pyridinium, quinolinium or isoquinolinium group, e.g., .sup..sym. R.sub.1 is a 3- or 4-formylpyridinium oxime group; pharmaceutical compositions comprising the antibiotic, and a method for treating antibacterial infections are provided.

REFERENCES:
patent: 4200575 (1980-04-01), Numata et al.
patent: 4258041 (1981-03-01), O'Callaghan et al.
patent: 4267176 (1981-05-01), Kamiya et al.
Nomura et al., J. Med. Chem. 1974, vol. 17, No. 12, pp. 1312-1315.
Derwent Abstract 32890.

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