Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1999-03-30
2000-02-01
Cook, Rebecca
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514558, A61K 3120
Patent
active
060203781
ABSTRACT:
A method for treating an animal to reduce body fat while the animal exhibits improved feed efficiency and either continued weight gain or an increase in lean body mass includes the steps of administering to the animal a combination of CLA isomers in a ratio selected to retain a desirable benefit attributable to one isomer while counteracting an undesirable effect of the same isomer.
REFERENCES:
patent: 5017614 (1991-05-01), Pariza et al.
patent: 5070104 (1991-12-01), Pariza et al.
patent: 5428072 (1995-06-01), Cook et al.
patent: 5430066 (1995-07-01), Cook et al.
patent: 5554646 (1996-09-01), Cook et al.
patent: 5760082 (1998-06-01), Cook et al.
patent: 5851572 (1998-12-01), Cook et al.
Belury et al., "Conjugated Linoleic Acid Modulates Hepatic Lipid Composition in Mice", Lipids, 32:199-204 (1997).
Cesano et al., "Opposite Effects of Linoleic Acid and Conjugated Linoleic Acid on Human Prostatic Cancer in SCID Mice", Anticancer Research 18:1429-1434(1998).
Chen et al., "Chemoenzymatic Synthesis of Conjugated Linoleic Acid", J. Org. Chem. 63:9620-9621 (1998).
Chin et al, "Conjugated Linoleic Acid is a Growth Factor for Rats as Shown by Enhanced Weight Gain and Improved Feed Efficiency", J. Nutri. 124:2344-2349 (1994).
Chin et al., "Dietary Sources of Conjugated Dienoic Isomers of Linoleic Acid, a Newly Recognized Class of Anticarcinogens", J. of Food Composition and Analysis 5:185-197 (1992).
Fogerty et al., "Octadeca-9,11-Dienoic Acid in Foodstuffs and in the Lipids of Human Blood and Breast Milk", Nutrition Reports International 38:937-942 (1988).
Gurr, "A Trans Fatty Acid that is Good to Eat? Conjugated Linoleic Acid", Lipid Technology 7(6):133-135 (1995).
Ha et al., "Inhibtion of Benzo(.alpha.)Pyrene-Induced Mouse Forestomach Neoplasia by Conjugated Dienoic Derivatives of Linoleic Acid", Cancer Research 50:1097-1101 (1990).
Ha et al., "Anticarcinogens from Fried Ground Beef: Heat-Altered Derivatives of Linoleic Acid", Carcinogenesis, 8(12):1881-1887 (1987).
Ha et al., "Newly Recognized Anticarcinogenic Fatty Acids: Identification and Quantification in Natural and Processed Cheeses", J. Agric. Food Chem., 37(1): 75-81 (1989).
Hayek et al., "Dietary Conjugated Linoleic Acid Influences the Immune Response of Young and Old C57BL/6NCrlBR Mice.", J. Nutri., 129: 32-38 (1999).
Ip et al., "Mammary Cancer Prevention by Conjugated Dienoic Derivative of Linoleic Acid", Cancer Research 51:6118-6124 (1991).
Kammerlehner, J. "Linolsaure und Konjugierte Linolsauren-ihr Vorkommen im Milchfett, ihre Biologische Bedeutung", DMZ Lebensmittelindustrie Und Milchinhaltsstoffe 116(26):1268-1272 (1995).
Lin et al., "Survey of the Conjugated Linoleic Acid Contents of Dairy Products", J. Dairy Sci. 78(11):2358-2365 (1995).
McGuire, "Conjugated Linoleic Acid Concentration of Human Milk and Infant Formulae", FASEB J. 10(3):A553 (1996).
Miller et al., "Feeding Conjugated Linoleic Acid to Animals Partially Overcomes Catabolic Responses Due to Endotoxin Injection", Biochemical and Biophysical Research Communications 198(3):1107-1112 (1994).
Pariza et al., "Conjugated Linoleic Acid (CLA) Reduces Body Fat", FASEB Journal 10(3):A560 (1996).
Pariza, M.W., "CLA, A New Cancer Inhibitor in Dairy Products", Bulletin of the IDF 257:29-30(1991).
Pariza, M.W., Food Research Institute 1988 Annual Fall Meeting, Oct. 12, 1998.
Pariza, M.W., "Designer Foods: Effects on Development of Cancer", J. National Cancer Institute Monographs 12:105-107 (1992).
Pariza, M.W., "Report of the Council on Scientific Affairs", Archives of Internal Medicine, 153:50-56 (1993).
Pariza, M.W., "CLA and HEMF: Newly Recognized Anticarcinogenic Antioxidants", Active Oxygens, Lipid Peroxides, and Antioxidants (Yagi, K. ed., 359-365, Japan Sci. Soc. Press. Tokyo/CRC Press, Boca Raton (1993).
Park et al., "Effect of Conjugated Linoleic Acid on Body Composition in Mice", Lipids 32(8):853-858 (1997).
Sarkar, G., "Beneficial ghee?" Nature 352:673 (1991).
Shantha et al., "Conjugated Linoelic Acid Concentrations in Processed Cheese Containing Hydrogen Donors, Iron and Dairy-Based Additives", Food Chemistry 47:257-261 (1993).
Shanatha et al., "Conjugated Linoleic Acid Concentrations in Dairy Products as Affected by Processing and Storage", J. Food Science 60(4):695-720 (1995).
Sieber. R., "Konjugierte Linolsauren in Lebensmitteln: eine Ubersicht", Ernahrung/Nutrition 19:265-270 (1996).
Silvis et al., "Nutritional Recommendations for Individuals with Diabetes Mellitus," South African Med. J. 81:162-166 (1992).
The Merck Index, Tenth Edition p. 790 (1983).
The Merck Veterinary Manual, Fifth Edition, pp. 1340-1343 and 1374-1379 (1979).
West et al., "Effects of Conjugated Linoleic Acid on Body Fat and Energy Metabolism in the Mouse", Am. J. Physiol., 275 (Regulatory Integrative Comp. Physiol. 44): R667-R672 (1998).
Weyman, C. et al., "Linoleic Acid as an Immunosuppressive Agent," Lancet, 2(7923):33 (1975).
Wong et al., "Effects of Dietary Conjugated Linoleic Acid on Lymphocyte Function and Growth of Mammary Tumors in Mice", Anticancer Research, 17:987-994 (1997).
Cook Mark E.
Jerome Daria
Pariza Michael W.
Cook Rebecca
Wisconsin Alumni Research Foundation
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