Anticancer property of dithiolopyrrolones

Details Anticancer property of dithiolopyrrolones Anticancer property of dithiolopyrrolones

1996-09-18

2000-02-01

Goldberg, Jerome

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3140

Patent

active

060203609

ABSTRACT:
The invention is drawn to a novel use of a group of known compounds with the formula shown below, ##STR1## wherein R.sub.1, R.sub.2 =hydrogen, substituted or unsubstituted alkyl, cycloalkyl, acyl, aryl, aralkyl, or heterocyclic group; R.sub.3 =hydrogen, alkyl, cycloalkyl, aralkyl, aryl or heterocyclic group, the salts thereof, the compositions thereof and their use as medicaments, particularly in the treatment of human and animal cancers.

REFERENCES:
Arnold, J. T. et al., 1995. Cancer Research 55:537-543.
Celmer, W. D. and I. A. Solomons 1955. J. Amer. Chem. Soc. 77:2861-2865.
Eisenman, W. et al., 1953. Antibiotics and Chemotherapy 3: 385-392.
Forst, S. and K. Nealson, 1996. Microbiol. Rev. 60:21-43.
Hagio, K. and Yoneda, N. 1974. Bull. Chem. Soc. Japan. 47:1484-1489.
Jimenez, A. et al., 1973, Antimicrob. Ag. Chemother. 729-738.
Li, J. et al., 1995. J. Nat. Prod. 58:1081-1085.
McInerney, B. V. et al., 1991. J. Nat. Prod. 54:774-784.
Menta R. G. and R. C. Moon, 1991. Anticancer Research 11:593-596.
Ninomiya, Y. T. et al., 1980. Chem. Pharm. Bull. 28:3157-3162.
Sharma, S. et al., 1994. Cancer Research 54:5848-5855.
Skehan, P. et al., 1990. J. Natl. Cancer Inst 82:1107-1118.
Stachel, H.D. et al. 1992. Liebigs Ann. Chem. 473-480. (Abstract only).
Tipper D.J. 1973, J. Bacteriol. 116:245-256.
Umezawa, H. et al. 1948. Jap. Med. J. 1:512-517.
von Daehne, W. et al., 1969. J. Antibiotics 22:233-235.
Mehta et al., Anticancer Res (1991) 11(2), 593-6 The Original Article to Follow in Due Course.

Affiliated with

Also associated with

Rating

Anticancer property of dithiolopyrrolones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anticancer property of dithiolopyrrolones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anticancer property of dithiolopyrrolones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-937904