Process for producing an optically active .alpha.-isopropyl-p-ch

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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562196, C07C 6976

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active

049837583

ABSTRACT:
A process for producing an optically active .alpha.-isopropyl-p-chlorophenylacetic acid (ICPA) of the formula: ##STR1## wherein the symbol * stands for an asymmetric carbon atom.

REFERENCES:
patent: 4277494 (1981-07-01), Faroog et al.
Chemical Abstract CA 110(15) 134950h 1988.
Chemical Abstract CA 110 (9) 74510c 1988.
Optical Resolution of 2-(4-Chlorophenyl)-3-Methylbutanoic Acid by Preferential Crystallization with Achiral Amines by Hiroyuki Nohira, Daiyo Terunuma and Sinji Kobe pp. 1421 to 1423.
Isomerization-Crystallization Method in Optical Resolution by Kazutaka Arai, pp. 486 to 498.
Enantiomers, Racemates, and Resolutions, by J. Jacques et al. pp. 43 thru 89.
Optical Resolution of 2-(4-substituted Phenyl)-3-Methylbutanoic Acids with Diethylamine by Preferential Crystallization by Hiroyuki Nohira, Daiyo Terunuma, Shinzi Kobe, Ikuko Asakura, Akira Miyashita and Tasuku Ito Sep. 17, 1985; pp. 675 thru 681.

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