Preparation of 5-(arylcyanohydroxymethyl)-1-loweralkylpyrrole-2-

Details Preparation of 5-(arylcyanohydroxymethyl)-1-loweralkylpyrrole-2- Preparation of 5-(arylcyanohydroxymethyl)-1-loweralkylpyrrole-2-

1980-04-17

1981-10-13

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603265R, 2603265S, 260545R, C07D207337

Patent

active

042947600

ABSTRACT:
5-(Arylcyanohydroxymethyl)-1-loweralkylpyrrole-2-acetic acid derivatives are prepared by the protic acid catalyzed reaction of aroylcyanides with 1-loweralkylpyrrole-2-acetic acid derivatives, which is then converted by treatment with alkali metal hydroxides or heat to form 5-aroyl-1-loweralkylpyrrole-2-acetic acid or derivatives thereof.

REFERENCES:
patent: 4255335 (1981-03-01), Carson
Jones et al., The Chemistry of Pyrroles, (Academic Press, N.Y., 1977), pp. 164-166, 169-172, 304.
Selikson et al., J. Org. Chem., vol. 40, pp. 267-268 (1975).

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