Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-04-28
1980-05-13
Evans, Joseph E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602391, 424246, 424271, A61K 3143, C07D49968
Patent
active
042029007
ABSTRACT:
6-Acylamino-penam-3-carboxylic acids and 7-acylamino-3-cephem-4-carboxylic acids in which the acyl group has the formula ##STR1## in which R.sub.1 is hydrogen, R.sub.2 is optionally substituted phenyl, thienyl or furyl or R.sub.1 and R.sub.2 together are optionally substituted cycloalkyl, n and m independently of one another represent 0 or 1 and B represents an optionally substituted 2,6-dioxo- or 2,6-dithioxo-1,2,3,6-tetrahydro-pyrimidyl, 2-thioxo-6-oxo-1,2,3,6-tetrahydropyrimidyl, 2,6-dihydroxy- or 2,6-dimercapto-pyrimidyl, 2-mercapto-6-hydroxy-pyrimidyl, 2,6-diaminopyrimidyl, 2-amino-6-hydroxy-pyrimidyl or 2,6-dihalogenopyrimidyl radical, these radicals being bonded in the 4- or 5-position.
REFERENCES:
patent: 3433784 (1969-03-01), Long et al.
patent: 3953428 (1976-04-01), Murakami et al.
patent: 4008220 (1977-02-01), Tobiki et al.
patent: 4015000 (1977-03-01), Kocsis et al.
Bickel Hans
Fechtig Bruno
Kocsis Karoly
Ciba-Geigy Corporation
Clarke Vera C.
Evans Joseph E.
Maitner John J.
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