1-Polyhaloalkyl-2(1H)-quinazolinone derivatives

Details 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives

1974-06-14

1980-05-13

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544286, A61K 31505, C07D23982

Patent

active

042028957

ABSTRACT:
1-Polyhaloalkyl-2(1H)-quinazoline derivatives of the formula, ##STR1## wherein R is polyhaloalkyl having C.sub.2 -C.sub.4 alkyl; and R.sub.1, R.sub.2 and R.sub.3 are individually hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, trifluoromethyl or halogen, have excellent anti-inflammatory and analgesic activities with very low toxicity. These quinazolinone derivatives can be prepared, for example, by reacting a trihalogenoacetamidobenzophenone derivative with ammonia.

REFERENCES:
patent: 3549635 (1970-12-01), Ott
patent: 3551427 (1970-12-01), Ott
patent: 3712892 (1973-01-01), Inaba et al.
patent: 3812118 (1974-05-01), Yamamoto et al.
patent: 3829420 (1974-08-01), Inaba et al.
patent: 3859237 (1975-01-01), Inaba et al.
patent: 3910911 (1975-10-01), Ishizumi et al.
patent: 3923710 (1975-12-01), Ishizumi et al.
patent: 3925382 (1975-12-01), Ishizumi et al.
patent: 3926993 (1975-12-01), Ishizumi et al.
patent: 3953446 (1976-04-01), Ishizumi et al.
Yamamoto et al. (II)--C.A. 78, 72196b (1973).
Yamamoto et al. (III)--C.A. 79, 149319z (1973).

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