Method for enhancing the systemic delivery of dextromethorphan f

Details Method for enhancing the systemic delivery of dextromethorphan f Method for enhancing the systemic delivery of dextromethorphan f

1991-06-17

1992-11-24

Friedman, S. J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61U 31515

Patent

active

051662078

ABSTRACT:
A method for enhancing the systemic delivery of dextromethorphan for the treatment of a neurological disorder resulting in injury to nervous tissue, which comprises administering to a patient suffering from the disorder an amount of a cytochrome P450IID6 enzyme inhibitor, sufficient to block dextromethorphan metabolism, and an amount of dextromethorphan sufficient to treat the neurological disorder. Quinidine is particularly suitable for use in the method of the invention.

REFERENCES:
Chem. Abst. 111-89742z, (1989).

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