Substituted pyrimidines, pyrimidinones and pyridopyrimidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 86, 514272, 514273, 514274, 544243, 544297, 544299, 544300, 544301, 544302, 544303, 544309, 544310, 544311, 544312, 544313, 544314, 544315, 544316, 544317, 544318, 544319, 544321, 544323, 544324, 544325, 544326, 544327, 544328, 544329, 544330, 544331, 544332, A61K 31505, C07D23902, C07D23922, C07D23946, C07F 902

Patent

active

051662060

ABSTRACT:
Substituted pyrimidines, pyrimidinones and pyridopyrimidines of formula (I) are as angiotensin II antagonists useful in the treatment of hypertension, ocular hypertension and certain CNS ailments: ##STR1## wherein K is --N(R.sup.8a)--C(.dbd.M) or --N.dbd.C(R.sup.8b) where M is O or NR.sup.22.

REFERENCES:
patent: 4207324 (1980-06-01), Matsumura et al.
patent: 4340598 (1982-07-01), Furukawa et al.
patent: 4576958 (1986-03-01), Wexler
patent: 4582847 (1986-04-01), Furukawa et al.

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