Use of relaxin in cardiovascular therapy

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530324, A61K 3702, C07K 740

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active

051661918

ABSTRACT:
The invention concerns the use of relaxin in the cardiovascular therapy, and specifically in the treatment of acute and chronic heart failure.

REFERENCES:
patent: 4656249 (1987-04-01), Tregear
patent: 4758516 (1988-07-01), Hudson et al.
patent: 4835251 (1989-05-01), Burnier
patent: 4871670 (1989-10-01), Hudson et al.
patent: 5023321 (1991-06-01), Hudson et al.
Sherwood, O. D., The Physiology of Reproduction, Chapter 16 "Relaxin", Knobil, E. and Neill, J. et al. (eds.) Raven Press, Ltd. New York, 1988, pp. 585-673.
Isaacs et al., Nature 271, 278 (1978).
Weiss et al., Chem. Abstr. 88, 224 88:71076g (1978).
Bigazzi et al., Chem. Abstr. 95, 366 95:12753x (1981).
Hudson et al., Nature 301, 628 (1983).
Hudson et al., EMBO J. 3, 2333 (1984).
Tregear et al., Relaxin, Bryant-Greenwood, Niall and Greenwood (eds.), Elsevier, 1981, pp. 152-164.
Johnston et al., in Peptides: Structure and Function, Proc. Ninth Am. Peptide Symp., Deber, C. M. et al. (eds.), Pierce Chem. Co. 1985.
Tregear et al., in Biology of Relaxin and its Role in the Human, Bigazzi et al. (eds.) Elsevier N.Y., N.Y. 42-55.
O'Byrne et al., J. Clin. Endocr. and Metabol. 47, 1106 (1978).
Sherwood et al., Endocrinology 107, 691 (1980).
Bell et al., Obstet. Gynecol. 69, 585 (1987).
Stewart et al., J. Clin. Endo. Metab. 70, 1771 (1990).
Aoi et al., Proc. Soc. for Exp. Biol. and Med. 153, 13 (1976).
Chesley, C. C., Hypertensive Disorders in Pregnancy, Appleton Century-Crofts publ. 119-153 (1978).
Moutquin et al., J. Gyn. Obst. Biol. Rep., 11, 833 (1982).
Clapp, J. F., Am. J. Obstet. Gynecol. 152, 659 (1985).
Massicotte et al., Clin. and Exp. Hyper.-Hyper. in Pregnancy B5(2), 135 (1986).
Robson et al., Am. J. Physiol. 256, H1060 (1989).
Miller et al., J. Pharmacol. Exp. Ther. 120, 426 (1957).
Braddon, S. A., Endocrinology 102, 1291 (1978).
Porter et al., J. Endocr. 83, 18 (1979).
Sanborn et al., Endocrinology 106, 1210 (1980).
Judson et al., J. Endocr. 87, 153 (1980).
Nishikoro et al., Endocrinology 111, 1743 (1982).
Nishikori et al., J. Biol. Chem. 258, 2468 (1983).
Del Mese et al., in "Biology of Relaxin and its Role in the Human", Bigazzi et al. (eds.), 291-293 (1983).
St-Louis, J. and Massicotte, G., Life Sciences 37, 1351 (1985).
O' Byrne et al., J. Physiol. 561, 49P (1985).
Bigazzi et al., Acta Endocrinol. 112, 296 (1986).
Jones, S. A. and Summerlee, A. J. S., J. Physiol. 381, 37P (1986).
O'Byrne et al., J. Endocr. 109, 393 (1986).
Cronin et al., Biochem. Biophys. Res. Comm. 148, 1246 (1987).
Jones, S. A. and Summerlee, A. J. S., J. Endocr. 114, 241 (1987).
Dayanithi et al., Nature 325, 813 (1987).
Massicotte et al., P.S.E.M.B. 190, 254 (1988).
Chen et al., Biol. Reprod. 39, 519 (1988).
Mumford et al., J. Endocrinol. 122, 747 (1989).
Ahokas et al., Am. J. Obstet. Gynecol. 161, 618 (1989).
Parry et al., J. Neuroendocrinol. 2, 53 (1990).
Parry et al., Endocrinol. 129, 47 (1991).
Kramer et al., In Vitro Cell. Dev. Biol. 26, 647 (1990).
Ward et al., Am. J. Physiol. 261, H206 (1991).
Casten et al., Angiology XI, 408 (1960).
Casten et al., J.A.M.A. 166, 319 (1958).
Ward et al., Genentech Reports No. 88-485-350-561 (1989).
Mercado-Simmen et al., J. Biol. Chem. 255, 3617 (1980).
Mercado-Simmen et al., Biology of Reproduction 26, 120 (1982).
Mercado-Simmen et al., Endocrin. 110, 220 (1982).
Osheroff, P. L., J. Biol. Chem. 265, 9396 (1990).
Osheroff, P. L. and Phillips, H. S., Proc. Natl. Acad. Sci. 88, 6413 (1991).
Schramm et al., Arzneim-Forsch. 33, 1268 (1983).
Evans et al., Pharmacologist 25, 550 (1983).
Evans et al., Drug Develop. Res. 9, 143 (1986).
Taylor et al., Ann. Rep. in Med. Chem. 22, 85 (1987).
Weishaar et al., Cardiovasc. Drugs and Ther. 3, 29 (1989).
Steffen et al., J. Cardiovasc. Res. 9,143 (1986).
Steffen et al., New Cardiovascular Drugs, Raven Press, New York, p. 81 (1986).

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