Gene therapy using gene fusions for genetic or acquired disorder

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 435 91, 4351723, 4352351, 4353201, 4352402, 536 27, 530350, 935 10, 935 32, 935 34, 935 57, 935 62, 935 70, C12P 2102, C12P 1934, C12N 1500, C12N 700

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active

051660598

ABSTRACT:
Gene therapy utilizing an MDR1 linked fusion coding sequence has been disclosed. ADA activity has been introduced into cells using MDR1 linked fusion gene.

REFERENCES:
patent: 4704362 (1987-11-01), Itakura et al.
Gross et al., Proc. Natl. Acad. Sci. USA vol. 83 pp. 337-341 (1986).
Williams et al., Proc. Natl. Acad. Sci., USA, vol. 83, pp. 2566-2570 (1986).
Veda et al., Proc. Natl. Acad. Sci. vol. 84 pp. 3004-3008 (1987).

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