Treatment of acne and dandruff

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil

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424279, 424285, 424316, 424317, 424320, 424DIG4, A61K 3135

Patent

active

041057821

ABSTRACT:
Preventive as well as therapeutic treatment to alleviate the symptoms of diseases characterized by defects in keratinization consisting of the topical application of a solution, lotion, cream or shampoo containing one or more of the .alpha.-hydroxy or .alpha.-keto acid amides and/or ammonium salts is disclosed. The compounds include amide and/or ammonium salt forms of citric acid, glycolic acid, glucuronic acid, galacturonic acid, glucuronolactone, gluconolactone, .alpha.-hydroxybutyric acid, .alpha.-hydroxyisobutyric acid, malic acid, mandelic acid, pyruvic acid, .beta.-phenyllactic acid, .beta.-phenylpyruvic acid, saccharic acid, tartaric acid, tartronic acid and .beta.-hydroxybutyric acid. The therapeutic composition may include one or more of the compounds present in a total amount of from 1 to 20 percent. Topical application to affected areas has been found to achieve from a substantial to a complete remission of dandruff and acne.

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patent: 3879537 (1975-04-01), Van Scott et al.

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