Inhibition of indoleamine-N-methyl transferase by 2-iminopyridin

Details Inhibition of indoleamine-N-methyl transferase by 2-iminopyridin Inhibition of indoleamine-N-methyl transferase by 2-iminopyridin

1977-01-24

1978-08-08

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260296R, 260297Z, 26032685, A61K 3144, C07D21172

Patent

active

041057694

ABSTRACT:
A method of inhibiting indoleamine-N-methyl transferase comprises the administration to a host of a therapeutically effective amount of 1-alkyl-2-iminopyrrolidines or 1-alkyl-2-iminopyridines or pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 2810726 (1957-10-01), Howard
Foye, W. O., et al., J. Pharm. Sci., 57(2), 345-348 (1968).
Curphey, T. J., Organic Syntheses, R. E. Benson, ed., vol. 51, John Wiley and Sons, New York, 1971, pp. 144-146.
Vogel, E., et al., Justus Liebigs Ann. Chem., 682, 11 (1965).

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