Antibacterial 1,8-bridged 4-quinolone-3-carboxylic acids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540543, 540546, 540550, 540556, 540581, 544 6, 544 14, 544 32, 544 71, 544 99, 544101, 544230, 544343, 544344, 546 15, 546 72, 546 93, 546 94, A61K 31535, C07D49806

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047628316

ABSTRACT:
A process for the preparation of a 1,8-bridged 4-quinolone-3-carboxylic acid of the formula ##STR1## wherein the substituents are defined hereinbelow. Some of the compound are new. The old and new compounds are antibacterials and promote animal growth.

REFERENCES:
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Chemical Abstracts, 102:166678b (1985)[Hayakawa, I. et al., Chem. Pharm. Bull., 1984, 32(12), 4907-13].
Chemical Abstracts, 101:55108a (1984) [EP 101,829, Hayakawa et al., 3/7/84].
Chemical Abstracts 98:198294a (1983) [JPN Kokai 57,203,085, 12/13/82].
Chemical Abstracts, 94:25624k (1981) [Stevens, P., J. Antimicrob. Chemother., 1980, 6(4), 535-42].
Patent Abstracts of Japan, vol. 7, Mar. 3, 1983, p. 154.
Patent Abstracts of Japan, vol. 7, Feb. 10, 1983, p. 150.

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