Process for production of 8,11-eicosadienoic acid using Mortiere

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435134, 435135, 435244, 4352551, C12P 740, C12P 762, C12P 764

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active

053765419

ABSTRACT:
A process for the production of 8,11-eicosadienoic acid or a lipid containing 8,11-eicosadienoic acid comprising the steps of, culturing a microorganism having an ability to produce an omega 9 type polyunsaturated fatty acid in a medium supplemented with a .DELTA.5 desaturase inhibitor, or adding a .DELTA.5 desaturase inhibitor to a medium in which said microorganism has been cultured and further culturing the microorganism to produce 8,11-eicosadienoic acid, or a lipid containing 8,11-eicosadienoic acid, and recovering the 8,11-eicosadienoic acid, or the lipid containing 8,11-eicosadienoic acid.

REFERENCES:
patent: 4916066 (1990-04-01), Akimoto et al.
patent: 5093249 (1992-03-01), Nakajima et al.
Pollero, R. J. et al, "Biosynthetic transformations of the eicosa-8,11-dienoic acid in Acanthamoeba castellanii," Chemical Abstracts, vol. 89, No. 23, Dec. 4, 1978.
Patent Abstracts of Japan, unexamined applns. c field vol. 15, No. 231, Jun. 12, 1991 The Patent Office Japanese Govt., p. 148 C 840 No. 3-72 892 (Idemitsu Petrochem.).

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