Process for preparing 3-N-monosubstituted amino-4-substituted-5-

Details Process for preparing 3-N-monosubstituted amino-4-substituted-5- Process for preparing 3-N-monosubstituted amino-4-substituted-5-

1977-01-31

1978-08-08

Jaisle, Cecilia M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

544270, 544277, 544316, 544319, 544276, 544328, 544238, 544237, 260295L, 260305, 260308R, 260308B, 548327, 548336, 548359, 548360, C07D23116

Patent

active

041056566

ABSTRACT:
A process for preparing a 3-N-mono-substituted amino-4-substituted-5-pyrazolone which comprises replacing the hydrogen atom of the NH group at the 3-position of a 3-mono-substituted-5-pyrazolone with a protective group, halogenating the resulting compound to introduce a halogen atom into the 4-position, reacting the resulting compound with a 5- or 6-member heterocyclic compound containing two or more nitrogen atoms to replace the halogen atom at the 4-position with a nitrogen containing heterocyclic group, and hydrolyzing the resulting compound to remove the protective group.

REFERENCES:
patent: 3935262 (1976-01-01), Lestina
patent: 3956339 (1976-05-01), Furutachi

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