Thiomethylpyridine derivatives and their use for eliciting a bro

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514258, 514302, 514312, 514339, 514341, 544253, 544262, 544315, 544318, 546157, 546256, 546270, 546271, 546275, 546276, 546339, A61K 31505, C07D48706, C07D40112, C07D41312

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048660663

ABSTRACT:
Thiomethylpyridine derivatives having bronchosecretolytic and mucolytic activity according to the formula: ##STR1## wherein R is a group attached in the 2-, 3- or 4-position of the pyridine ring which corresponds to the following general formula:

REFERENCES:
Eichler et al., CA 99-70626b.
Schickaneder et al., CA 106-138391s.
Tweit et al., CA 80-420, p. 1974.
Haviv et al., J. Med. Chem., 1983, vol. 26, No. 2, pp. 218-222.
Schickaneder et al., J. Med. Chem., 1987, 30, pp. 547-551.
Schickaneder et al., CA 100-68183a.
Haviv et al., CA 98-46446b.

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