Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-01-09
1985-07-09
Chan, Nicky
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D31168
Patent
active
045283877
ABSTRACT:
Sorbinil is obtained by cyclization of S-6-fluoro-4-ureidochromane-4-carboxylic acid, which is in turn obtained by resolution of racemic 6-fluoro-4-ureidochroman-4-carboxylic acid via diasteromeric salts with either D-(+)-(1-phenethyl)amine or L-(-)-ephedrine.
REFERENCES:
patent: 4117230 (1978-09-01), Sarges
patent: 4130714 (1978-12-01), Sarges
patent: 4286098 (1981-08-01), Sarges
patent: 4348526 (1982-09-01), Sarges
Sarges, R., et al., J. Org. Chem., 47, pp. 4081-4085, Oct. 8, 1982.
Cue, Jr. Berkeley W.
Moore Bernard S.
Blackwood Robert K.
Chan Nicky
Frost Albert F.
Knuth Charles J.
Pfizer Inc.
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