Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D31168

Patent

active

045283877

ABSTRACT:
Sorbinil is obtained by cyclization of S-6-fluoro-4-ureidochromane-4-carboxylic acid, which is in turn obtained by resolution of racemic 6-fluoro-4-ureidochroman-4-carboxylic acid via diasteromeric salts with either D-(+)-(1-phenethyl)amine or L-(-)-ephedrine.

REFERENCES:
patent: 4117230 (1978-09-01), Sarges
patent: 4130714 (1978-12-01), Sarges
patent: 4286098 (1981-08-01), Sarges
patent: 4348526 (1982-09-01), Sarges
Sarges, R., et al., J. Org. Chem., 47, pp. 4081-4085, Oct. 8, 1982.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochr will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-910251

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.