Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1991-05-23
1992-10-27
Tsang, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514337, 514371, 514431, 546274, 548134, 548136, 548195, 5483114, 5483117, 548447, 549 5, 549 12, A61K 3167, A61K 3138, C07D33712, C07D40900
Patent
active
051589435
ABSTRACT:
A sulfur-containing hetrocyclic compound of the formula (I) ##STR1## wherein the ring A is an optionally substituted benzene ring, R is a hydrogen atom or an optionally substituted hydrocarbon residue, B is a carboxyl group which may be esterified or amidated, X is --CH(OH)-- or --CO--, and n is an integer of 0, 1 or 2, or its salt, which is useful in the prevention or treatment of osteoporosis.
REFERENCES:
March, Advanced Organic Chemistry, 3rd Edition, p. 484, reaction 1-15.
R. Adams, Organic Reactions, 2, p. 114 (1962).
Shin Jikken Kagaku Koza 15 Oxidization and Reduction (II).
Chem. Pharm. Bull., 30, p. 3580 (1982).
Chem. Pharm. Bull. 30, p. 3601 (1982).
Neher et al., CA 73-28902b (1970).
Hori et al., CA 111-779407 (1989).
P. H. Bell et al., JACS, vol. 90, p. 2704 (1968).
Sohda Takashi
Yamazaki Iwao
Takeda Chemical Industries Ltd.
Tsang Cecilia
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