Substituted (5,6,e) indoles

Details Substituted (5,6,e) indoles Substituted (5,6,e) indoles

1974-03-21

1976-05-25

Friedman, Stanley J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260246R, C07D27900, C07D28500, C07D29500

Patent

active

039592707

ABSTRACT:
A compound of the formula ##SPC1##
Wherein R.sub.1 is alkyl having one to 4 carbon atoms, and R.sub.2 is (a) alkyl having one to 4 carbon atoms, or (b) alkyl having one to 4 carbon atoms and substituted by (1) dialkylamino the latter alkyl having from one to 3 carbon atoms, (2) pyrrolidino or (3) morpholino, with the proviso that when R.sub.1 is ethyl, R.sub.2 is not ethyl, propyl, or diethylamino. The compounds are prepared by reacting 2-methyl-3-alkoxycarbonyl-5-hydroxyindole with a primary amine. The compounds possess diuretic, antihypertensive, antiulcerous, antiinflammatory, sedative and analgesic properties.

REFERENCES:
grino et al., Chem. Abstracts, Vol. 74, (Item 22645), (1971).

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