Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1990-05-17
1992-10-27
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424484, 424449, 514813, 131297, 131347, A61K 31465, A24B 1500
Patent
active
051587718
DESCRIPTION:
BRIEF SUMMARY
FIELD OF INVENTION
This invention relates to a composition having application in assisting cigarette smokers to abandon their habit.
BACKGROUND OF THE INVENTION
Conventionally, the top leaves of the tobacco plant are harvested at an appropriate time and these are cured and processed for use by smokers. The maturing of leaves, and the temperatures during smoking, generate many different and harmful chemicals. Smoking cigarettes has been linked with lung cancer, cardiovascular diseases, etc. There are many proposals by which those who smoke may be assisted to avoid their habit, but none are universally effective.
OBJECT OF THE INVENTION
It is an object of the present invention to provide a composition which may be utilised by persons who require the stimulus that is the motivation for smoking without the risks attendant to smoking. Other objects, and various advantages of the present invention will hereinafter become apparent.
In the production of smoking tobacco, and cigarettes therefrom, there results a product which incorporates a range of harmful chemicals that arise in the degradation processes undergone by the cut leaves during curing. The range of harmful chemicals is increased by the action of heat in the smoking process. The nicotine which the smoker craves is present in the tobacco leaves at the outset. It is not a product of maturation, curing or combustion, etc and it is these steps that need to be avoided. Typically, the present invention utilises sources such as tobacco leaves so as to generate a product whereby the user may obtain the object of smoking without undergoing the harmful side effects.
OUTLINE OF THE INVENTION
The invention provides a composition for use in the suppression of a smoking habit by dermal application of a tobacco suspension comprising between 0.1% and 8.0% of nicotine in a water based solvent.
The above composition for use in the suppression of a cigarette smoking habit may be provided in a roll-on container.
In methods for production of the above composition, dried but not cured or fresh picked tobacco leaves are utilised to produce the composition.
PREFERRED EMBODIMENTS OF THE INVENTION
The invention achieves its objects by provision of a liquid composition comprising a nicotine solution which may be applied to the user's skin, whereat, components within the composition, including nicotine, may be taken up by the body by a process of absorption.
The invention also provides a method of producing a tobacco composition by extracting nicotine from tobacco plants wherein:
tobacco leaves are mashed;
the mashed leaves are mixed with an aqueous solvent; and
the resulting liquid is decanted and filtered.
The dermal application is preferably achieved by use of a roll-on type applicator. The nicotine, in a liquid solution applied dermally from such a container, is readily taken up by the user through the skin.
In utilising tobacco leaves as a raw material for the composition, production is preferably performed upon the leaves soon after picking so as to lessen the amount of harmful degradation products. It is possible to process liquified plant materials so as to reduce or remove particular harmful components, and that way provide a product with greatly reduced concentrations of the chemical compounds that are being inhaled by cigarette smokers. By picking selected parts of the tobacco plant at selected times, and selectively processing the raw material, it is possible to generate a liquid tobacco composition that comprises a reduced range of harmful chemicals, by partial or complete removal, which when applied dermally poses none of the health problems facing smokers.
In a preferred embodiment the invention proposes to use tobacco leaves to generate a composition that retains the natural attributes of the plant; nicotine; proteins, chlorophylls; and several enzymes. Both these latter compounds are known to overcome carcinogenic effect of known carcinogens. On analysis of the green leaves of the tobacco plant that are utilised, uncured, in the process described belo
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SU, 301148, Besserezhnov) 24 Jun. 1971 abstract. Soviet Inventions Illustrated, Jan. 1971, Issued Jan. 1972, Section Ch: Chemical, Part 5 General Organic Chemistry --p. 22, published 1972, Derwent Pub. Ltd., London.
Rawal Bhupat
Spindler Frank R.
Page Thurman K.
Spear James M.
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