Process for removing endotoxin from biological fluids

Details Process for removing endotoxin from biological fluids Process for removing endotoxin from biological fluids

1974-12-27

1976-05-25

Hart, Charles N.

Liquid purification or separation

With alarm, indicator, register, recorder, signal or...

Responsive to fluid flow

128214R, 128DIG3, 210DIG23, 424 78, 424 83, 424101, B01D 1500

Patent

active

039591280

ABSTRACT:
A novel process for removing endotoxin from biological fluids such as parenteral fluids and for removing or reducing the level of endotoxin from the blood of animals is disclosed. The novel process includes the utilization of certain non-ionogenic hydrophobic synthetic plastic polymers that have been found to be capable of adsorbing endotoxin from the biological fluids when placed in intimate contact therewith.

REFERENCES:
patent: 3770631 (1973-11-01), Fekete et al.
patent: 3794584 (1974-02-01), Kunin
Hasselberger et al., "The Preparation of Insoluble, Matrix-supported Derivatives of Asparaginase for Use in Cancer Therapy", Cancer Research, Vol. 30, Nov. 1970, pp. 2736-2738.
Nolan et al., "Effect of Cholestyramine on Endotoxin Toxicity and Absorption", Digestive Diseases, Vol. 17, No. 2, Feb. 1972, pp. 161-166.

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