Pyridooxazinone-pyridazinone and pyrazolone compounds, cardioton

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514211, 514254, 514302, 540490, 540494, 544 91, 544105, 544238, 546116, A61K 31535, C07D49804

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active

048290661

ABSTRACT:
This invention relates to substituted pyridooxazinone pyridazinone and pyrazolone compounds, which are useful as cardiotonic agents for the treatment of congestive heart failure. This invention also relates to methods for increasing cardiac contractility using said compounds, and pharmaceutical compositions including said compound.

REFERENCES:
patent: 3854926 (1974-12-01), Senkbeil
patent: 3984405 (1976-10-01), Krapcho
patent: 4725686 (1988-02-01), Kuhla et al.
Heilmann et al., Chemical Abstracts, vol. 105 (1986), 226,602w.

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