Process for producing emitanin

Details Process for producing emitanin Process for producing emitanin

1978-02-27

1979-12-04

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 74, 435171, C12D 1300

Patent

active

041771087

ABSTRACT:
EMITANIN having antitumor activity is produced by inoculating mycelia of Tricholoma matsutake, Tricholoma baka-matsutake, Volvariella volvacea or Tremella fuciformis in a medium for growing mycelia and fermenting the grown mycelia in a liquid medium containing a carbohydrate and a nitrogen source and isolating solid substance of mycelia from a broth and extracting the solid substance of mycelia and isolating the active ingredient.

REFERENCES:
Ikekawa et al., Cancer Research, vol. 29, pp. 734-735 (1969).
Yoshioka et al., Chem. Pharm. Bull., vol. 20, pp. 1175-1180 (1972); vol. 21, pp. 1772-1776 (1973).
Ikekawa et al., Cancer Chemotherapy Reports Part I, 57, pp. 85-86 (1973).
Yoshioka et al., Carbohydrate Research 43, pp. 305-320 (1975).

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