Use of pyruvate and anti-cortisol compounds in a method for enha

Details Use of pyruvate and anti-cortisol compounds in a method for enha Use of pyruvate and anti-cortisol compounds in a method for enha

1998-02-23

1999-07-06

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 53, 514 78, A61K 3170, A61K 31715, A61K 31685

Patent

active

059197676

ABSTRACT:
The present invention is based, in part, upon the discovery that the use of pyruvate in combination with a cortisol blocker, such as phosphatidylserine, produces a synergistic effect in increasing lean body mass or muscle tissue, decreasing fat deposition, increasing endurance and athletic performance of a mammal consuming same. The invention also relates to a method of treating the catabolic effects of diseases such as cancer and AIDS by the administration of pyruvate and a cortisol blocker.
The present invention also discloses a synergistic composition comprising pyruvate and a cortisol blocker. More specifically, the present invention relates to a composition which comprises pyruvate and/or derivatives of pyruvate and phosphatidylserine.

REFERENCES:
patent: 5147650 (1992-09-01), Fregly et al.
patent: 5312985 (1994-05-01), Dhaon et al.
patent: 5472980 (1995-12-01), Miller
Fritz, "Phosphotidylserine--Have We Found a Medically Proven Cortisol Antagonist at Last?", IM, 74-75 Feb. 1996.
Brunner "HMB, ICIC and Leucine--Anticatabolic Body-Building Nutrients From the Same Branched Chain" IM 100-101. Jul. 1996.

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